Immunosuppressive macrolide antibiotic with structural similarity to FK 506; inhibits T- and B-cell proliferation but at a much later stage than FK 506, despite binding to the same immunophilin. Inhibits TOR (target of rapamycin) in the Ras/MAP kinase signalling pathway.

Dictionary of molecular biology. 2004.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Rapamycin — Strukturformel Allgemeines Freiname Sirolimus Andere Namen …   Deutsch Wikipedia

  • rapamycin — A drug used to help prevent the body from rejecting organ and bone marrow transplants. It is also being studied as a treatment for cancer. Rapamycin belongs to the family of drugs called immunosuppressants. It is now called sirolimus …   English dictionary of cancer terms

  • rapamycin — noun An immunosuppressant, extracted from Streptomyces hygroscopicus, used in tissue transplantation. Syn: sirolimus …   Wiktionary

  • rapamycin — rap·a·my·cin .rap ə mīs ən n an immunosuppressive agent C51H79NO13 * * * rap·a·my·cin (rap ə miґsin) sirolimus …   Medical dictionary

  • Mammalian target of rapamycin — Mechanistic target of rapamycin (serine/threonine kinase) PDB rendering based on 1aue …   Wikipedia

  • Mammalian Target of Rapamycin — MTOR Größe 2549 Aminosäuren Bezeichner Gen Name …   Deutsch Wikipedia

  • RAPA — rapamycin …   Medical dictionary

  • RAPA — • rapamycin …   Dictionary of medical acronyms & abbreviations

  • RICTOR — Rapamycin insensitive companion of mTOR, also known as RICTOR, is a human gene.cite web | title = Entrez Gene: RICTOR rapamycin insensitive companion of mTOR| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Rapamicina — Saltar a navegación, búsqueda Rapamicina …   Wikipedia Español

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”